More Randomization Problems
Randomized clinical trials (RCTs) are the “gold standard” for medical studies. Nevertheless, even RCTs have their problems. An NBER working paper by Ludwig, Marcotte and Norberg points highlights some...
View ArticleIncreasing Generalizability of RCTs
Is your randomized controlled trial (RCT) generalizable to the general population? This question is known as external validity and is a major issue for a number of treatments. Sometimes, a treatment...
View ArticleThe gold standard of scientific evidence
That is the title of my latest article in Pharmaceutical Market Europe. An excerpt is below. Randomised controlled trials (RCTs) are regarded as the gold standard of scientific evidence, and for good...
View ArticleTreatment effect heterogeneity, self-selection into RCTs, and racial disparities
In drug development, clinical trials typically aim for a population that is representative of the patients who would be eligible for the treatment. While randomized controlled trials (RCTs) typically...
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